What's there in GUILT?

I read some content in browser that

"Guilt is one of the main cause to suppress the prefrontal cortex functioning "

And It also reduces our intelligence and causes brain fog.

Can anyone tell me how guilt plays a very important role in suppressing the prefrontal cortex functioning?

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Guilt demotivates you and then cortisol hormone “the stress hormone” is released which mess up with your brain and then it decreases the learning capability,creativity which is controlled by the cerebellum which is the fore brain.

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